Design, Synthesis and in vitro Evaluation of Thiazole Derivatives of Ibuprofen as Cyclooxygenase-2 Inhibitors

Chang Bin GUO Zhe Feng CAI Zong Ru GUO Zhi Qiang FENG Feng Ming CHU Gui Fang CHENG

引用本文: Chang Bin GUO,  Zhe Feng CAI,  Zong Ru GUO,  Zhi Qiang FENG,  Feng Ming CHU,  Gui Fang CHENG. Design, Synthesis and in vitro Evaluation of Thiazole Derivatives of Ibuprofen as Cyclooxygenase-2 Inhibitors[J]. Chinese Chemical Letters, 2006, 17(3): 325-328. shu
Citation:  Chang Bin GUO,  Zhe Feng CAI,  Zong Ru GUO,  Zhi Qiang FENG,  Feng Ming CHU,  Gui Fang CHENG. Design, Synthesis and in vitro Evaluation of Thiazole Derivatives of Ibuprofen as Cyclooxygenase-2 Inhibitors[J]. Chinese Chemical Letters, 2006, 17(3): 325-328. shu

Design, Synthesis and in vitro Evaluation of Thiazole Derivatives of Ibuprofen as Cyclooxygenase-2 Inhibitors

  • 基金项目:

    This project was supported by the National Natural Science Foundation of China(No 39770877). We thank the analytical division of Institute of Materia Medica Chinese Academy of Medical Sciences for the spectroscopic measurement and elementary analysis.

摘要: A series of thiazole derivatives of ibuprofen, as cyclooxygenase-2 Inhibitors, were designed, synthesized and in vitro evaluated.

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  • 收稿日期:  2005-07-17
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