The applications of Schiff bases in Ti-catalyzed asymmetric alkynylation of aldehydes

Xian Jia Lu Yin Xuan Zhao Xing Shu Li

引用本文: Xian Jia,  Lu Yin,  Xuan Zhao,  Xing Shu Li. The applications of Schiff bases in Ti-catalyzed asymmetric alkynylation of aldehydes[J]. Chinese Chemical Letters, 2007, 18(3): 275-278. doi: 10.1016/j.cclet.2007.01.022 shu
Citation:  Xian Jia,  Lu Yin,  Xuan Zhao,  Xing Shu Li. The applications of Schiff bases in Ti-catalyzed asymmetric alkynylation of aldehydes[J]. Chinese Chemical Letters, 2007, 18(3): 275-278. doi: 10.1016/j.cclet.2007.01.022 shu

The applications of Schiff bases in Ti-catalyzed asymmetric alkynylation of aldehydes

  • 基金项目:

    This study is supported by the National Natural Science Foundation of China (No. 20472116),the Natural Science Foundation of Liaoning Province (No. 1050155) and Shenyang Pharmaceutical University Fund.

摘要: Sciff bases 1 and 2, which were derived from chiral aminoalcohols, were used as ligands in Ti-catalyzed asymmetric alkynylation of aldehydes. Good enantioselectivities (up to 88% ee) and high chemical yields (80-90%) were obtained.

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  • 收稿日期:  2006-09-22
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