磁性分子印迹微球的制备及其对熊果酸的选择性分离

引用本文: 张鑫, 李彦松, 汤波, 张浩, 焦朋飞, 韦宇平, 王鹏. 磁性分子印迹微球的制备及其对熊果酸的选择性分离[J]. 分析化学, 2021, 49(4): 628-635. doi: 10.19756/j.issn.0253-3820.201603 shu

Citation: ZHANG Xin, LI Yan-Song, TANG Bo, ZHANG Hao, JIAO Peng-Fei, WEI Yu-Ping, WANG Peng. Preparation of Magnetic Molecularly Imprinted Microspheres for Selective Separation of Ursolic Acid[J]. Chinese Journal of Analytical Chemistry, 2021, 49(4): 628-635. doi: 10.19756/j.issn.0253-3820.201603 shu

磁性分子印迹微球的制备及其对熊果酸的选择性分离

张鑫 ^{1,
,} ,
李彦松 ^1, ,
汤波 ^2, ,
张浩 ^1, ,
焦朋飞 ^1, ,
韦宇平 ^1, ,
王鹏 ^1,

1.
南阳师范学院生命与科学技术学院, 南阳 473061;
2.
北京理工大学生命学院, 北京 100081

通讯作者: 张鑫,E-mail:21588330@qq.com

基金项目:
河南省教育厅重点研究项目（No.20A180021）和南阳师范学院科研项目（No.2019ZX011）资助。

摘要: 利用表面分子印迹技术，以Fe₃O₄磁性纳米微球为基质材料、熊果酸为模板分子、3-氨丙基三乙氧基硅烷为功能单体、正硅酸乙酯为交联剂，制备了熊果酸磁性分子印迹纳米微球，用于熊果酸的高选择性快速分离。采用透射电子显微镜和振动样品磁强计对制备的复合纳米材料进行表征，通过吸附动力学和吸附等温线考察了制备的磁性分子印迹纳米微球的吸附性能。结果表明，磁性分子印迹纳米微球对熊果酸的最大吸附量为58.17 mg/g，印迹因子为3.65。此外，磁性分子印迹纳米微球具有良好的稳定性和重复利用率，回收率为96.5%~97.8%，RSD为2.2%~3.1%（n=5）。本研究制备的熊果酸磁性分子印迹微球具有操作简单、吸附速度快、吸附容量大、选择性高、环境友好的优点，适用于熊果酸的快速选择性分离提取。

关键词:

English

Preparation of Magnetic Molecularly Imprinted Microspheres for Selective Separation of Ursolic Acid

1.
School of Life Science and Technology, Nanyang Normal University, Nanyang 473061, China;
2.
School of Life Science, Beijing Institute of Technology, Beijing 100081, China

Corresponding author: ZHANG Xin, 21588330@qq.com

Received Date: 14 October 2020
Revised Date: 12 January 2021
Fund Project:
Supported by the Key Scientific Research Projects of Higher Education Institutions in Henan Province, China (No. 20A180021) and the Scientific Research Projects of Nanyang Normal University (No. 2019ZX011).

Abstract: The magnetic molecularly imprinted nanoparticles were prepared by surface molecular imprinting technology with Fe₃O₄ magnetic nanoparticles as matrix material, ursolic acid as template molecule and 3-aminopropyl triethoxysilane as functional monomer. The prepared magnetic molecularly imprinted nanoparticles were used for rapid separation of ursolic acid with high selectivity. These resulting nanocomposites were well characterized by transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM). The adsorption performance of the magnetic molecularly imprinted nanoparticles was investigated by adsorption kinetics and adsorptionisotherm experiments. Experimental results showed that the maximum adsorption capacity of the magnetic molecularly imprinted microspheres for ursolic acid was 58.17 mg/g, and the imprinting factor was 3.65. Moreover, the prepared magnetic molecularly imprinted nanospheres showed good stability and repeatability, and could be used for the adsorption of ursolic acid with recoveries of 96.5%-97.8% and RSD of 2.2%-3.1% (n=5). The proposed ursolic acid magnetic molecularly imprinted microspheres were demonstrated to be simple, environment friendly, and high sensitive in rapid separation and extraction of ursolic acid.

Key words:

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

磁性分子印迹微球的制备及其对熊果酸的选择性分离

通讯作者: 张鑫,E-mail:21588330@qq.com

English

Preparation of Magnetic Molecularly Imprinted Microspheres for Selective Separation of Ursolic Acid

Corresponding author: ZHANG Xin, 21588330@qq.com

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

磁性分子印迹微球的制备及其对熊果酸的选择性分离

通讯作者: 张鑫,E-mail:21588330@qq.com

English

Preparation of Magnetic Molecularly Imprinted Microspheres for Selective Separation of Ursolic Acid

Corresponding author: ZHANG Xin, 21588330@qq.com

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs