引用本文:
冯宗财, 李琳, 郭祀远, 胡松青. 固相载体法合成低聚糖[J]. 应用化学,
2006, 23(6): 659-662.
Citation: FENG Zong-Cai, LI Lin, GUO Si-Yuan, HU Song-Qing. Solid-phase Synthesis of Oligosaccharides[J]. Chinese Journal of Applied Chemistry, 2006, 23(6): 659-662.
Citation: FENG Zong-Cai, LI Lin, GUO Si-Yuan, HU Song-Qing. Solid-phase Synthesis of Oligosaccharides[J]. Chinese Journal of Applied Chemistry, 2006, 23(6): 659-662.
固相载体法合成低聚糖
English
Solid-phase Synthesis of Oligosaccharides
Abstract:
In the solid-phase synthesis of oligosaccharides,1,2-isopropyl-5,6-dehydrate-α,d-furan glucose was linked to the carriers styrene-diphenyl ethylene with sizes of 100~200 nm by dimethyldichlorosilane coupling agent.The saccharide chains were prolonged by the linkage of 1,2-isopropyl-5,6-dehydrate-α,d-furan glucose.In principle,the epoxy of the glucose unit on the carrier could react with the hydroxyl of another 1,2-isopropyl-5,6-dehydrate-α,d-furan glucose to make the target oligosaccharide.The resulant oligosaccharides were deattached from the carrier by tetrabutylammonium fluoride(TBAF) buffered with acetic acid and their structure was confirmed based on the results of UV,FT-IR,NMR and MS.
-
Key words:
- solid-phase carrier synthesis
- / oligosaccharide
- / coupling agent
-
-
扫一扫看文章
计量
- PDF下载量: 1
- 文章访问数: 286
- HTML全文浏览量: 37
下载:
