Synthesis, characterization and herbicidal activity of new thiazoline derivatives

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Synthesis, characterization and herbicidal activity of new thiazoline derivatives

Jian-Chao Liu , Ying Liang , Hong-Wu He

Citation: Jian-Chao Liu, Ying Liang, Hong-Wu He. Synthesis, characterization and herbicidal activity of new thiazoline derivatives[J]. Chinese Chemical Letters, 2013, 24(3): 233-235. shu

shu

Synthesis, characterization and herbicidal activity of new thiazoline derivatives

通讯作者: Hong-Wu He,

摘要: A series of new thiazoline derivatives 2-alkyl(aryl) imino-4-amino-5-ethoxycarbonyl-3-phenyl-3Hthiazoline (3) and bis(2-imino-4-amino-5-ethoxycarbonyl-3-phenyl-3H-thiazoline alkylene (4) have been synthesized by reactions of intermediate 4-amino-5-ethoxycarbonyl-2-methylthio-3-phenyl-3H-thiazolinium sulphate (2) with alkylamines or arylamine in 64%-89% yields. The structures of 3 and 4 have been confirmed by ¹H NMR, EI-MS, IR spectroscopy and elemental analyses. Some compounds exhibited high or moderate herbicidal activities against the roots of rapeseed and barnyard grass at 100 mg/L.

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English

Synthesis, characterization and herbicidal activity of new thiazoline derivatives

1.
a College of Chemistry, Central China Normal University, Wuhan 430079, China;
2.
b Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Science, Wuhan 430064, China

Corresponding author: Hong-Wu He,

Received Date: 19 November 2012
Available Online: 14 February 2013

Abstract: A series of new thiazoline derivatives 2-alkyl(aryl) imino-4-amino-5-ethoxycarbonyl-3-phenyl-3Hthiazoline (3) and bis(2-imino-4-amino-5-ethoxycarbonyl-3-phenyl-3H-thiazoline alkylene (4) have been synthesized by reactions of intermediate 4-amino-5-ethoxycarbonyl-2-methylthio-3-phenyl-3H-thiazolinium sulphate (2) with alkylamines or arylamine in 64%-89% yields. The structures of 3 and 4 have been confirmed by ¹H NMR, EI-MS, IR spectroscopy and elemental analyses. Some compounds exhibited high or moderate herbicidal activities against the roots of rapeseed and barnyard grass at 100 mg/L.

Key words:

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