原子转移自由基聚合在生物传感中的应用

引用本文: 李颖, 吴亚锋, 袁亮, 刘松琴. 原子转移自由基聚合在生物传感中的应用[J]. 分析化学, 2012, 40(12): 1797-1802. doi: 10.3724/SP.J.1096.2012.20531 shu

Citation: LI Ying, WU Ya-Feng, YUAN Liang, LIU Song-Qin. Application of Atom Transfer Radical Polymerization in Biosensing[J]. Chinese Journal of Analytical Chemistry, 2012, 40(12): 1797-1802. doi: 10.3724/SP.J.1096.2012.20531 shu

原子转移自由基聚合在生物传感中的应用

通讯作者: 刘松琴

基金项目:
本文系国家自然科学基金资助项目(No.20875013) (No.20875013)

摘要: 原子转移自由基聚合(ATRP)是一种新颖的信号放大方法。在聚合过程中,成百上千个单体分子聚集形成长链聚合物,聚合物的侧链可以修饰丰富的功能基团,可与电化学或光学活性物质发生键合反应,从而显著增加单元生物分子识别反应信号分子的负载量,提高了检测灵敏度,实现了生物分子检测的信号放大。本文综述了ATRP的反应机理及其近年来在生物传感中的应用,并展望了其发展前景。

关键词:

English

Application of Atom Transfer Radical Polymerization in Biosensing

1.
School of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, China

Corresponding author: 刘松琴

Received Date: 23 May 2012
Fund Project:
本文系国家自然科学基金资助项目(No.20875013)

Abstract: Atom transfer radical polymerization (ATRP) is a new class of signal amplification method. The polymer growth results in local accumulation of monomers to form long-chain polymers. The growth of long chain polymeric materials provides excess active groups for electroactive or photoactive molecules coupling, which in turn significantly increases the loading of signal molecules and enhanced detection sensitivity. This review introduced the mechanism of ATRP, summarized the recent application of ATRP in biosensing. Particularly, future study and prospect were envisioned.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

原子转移自由基聚合在生物传感中的应用

通讯作者: 刘松琴

English

Application of Atom Transfer Radical Polymerization in Biosensing

Corresponding author: 刘松琴

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

原子转移自由基聚合在生物传感中的应用

通讯作者: 刘松琴

English

Application of Atom Transfer Radical Polymerization in Biosensing

Corresponding author: 刘松琴

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

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