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金纳米粒子的细胞毒性

李铸衡 ,  马立娜 ,  刘殿骏 ,  王振新

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引用本文: 李铸衡, 马立娜, 刘殿骏, 王振新. 金纳米粒子的细胞毒性[J]. 应用化学, 2016, 33(9): 1009-1016. doi: 10.11944/j.issn.1000-0518.2016.09.160075 shu
Citation:  LI Zhuheng, MA Lina, LIU Dianjun, WANG Zhenxin. Cytotoxicity of Gold Nanoparticles[J]. Chinese Journal of Applied Chemistry, 2016, 33(9): 1009-1016. doi: 10.11944/j.issn.1000-0518.2016.09.160075 shu

金纳米粒子的细胞毒性

  • 1.

    a 吉林省教育学院 长春 130022;

  • 2.

    b 中国科学院长春应用化学研究所 长春 130022

    • 通讯作者: 王振新,教授;Tel/Fax:0431-85262243;E-mail:wangzx@ciac.ac.cn;研究方向:贵金属纳米粒子合成与应用;生物分析与生物分子相互作用;高通量分析
  • 基金项目:

    国家自然科学基金资助项目（21475126） 

摘要: 金纳米粒子（AuNPs）是构建用于诊断和治疗的纳米药物/探针的理想纳米材料之一，因此研究AuNPs与细胞的相互作用具有重要意义。本文详细分析了金纳米簇（AuNCs）、球形金纳米粒子A（AuNPss）、金纳米球壳（AuNSs）和金纳米棒（AuNRs）等不同形貌的Au NPs对不同细胞模型的细胞毒性；讨论了AuNPs的理化性质（大小、形状、化学功能和表面电荷）对其细胞毒性的影响。总结了AuNP细胞毒性研究遇到的挑战并提出相应解决方法。

English

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  • 收稿日期:  2016-02-29
  • 网络出版日期:  2016-04-20
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