2,3,3',4'-联苯四甲酸二酐的合成

李玉邯 吴强 康传清 郭海泉 金日哲 高连勋

引用本文: 李玉邯, 吴强, 康传清, 郭海泉, 金日哲, 高连勋. 2,3,3',4'-联苯四甲酸二酐的合成[J]. 应用化学, 2016, 33(8): 900-904. doi: 10.11944/j.issn.1000-0518.2016.08.150401 shu
Citation:  LI Yuhan, WU Qiang, KANG Chuanqing, GUO Haiquan, JIN Rizhe, GAO Lianxun. Synthesis of 2,3,3',4'-Biphenyltetracarboxylic Dianhydride[J]. Chinese Journal of Applied Chemistry, 2016, 33(8): 900-904. doi: 10.11944/j.issn.1000-0518.2016.08.150401 shu

2,3,3',4'-联苯四甲酸二酐的合成

    通讯作者: 金日哲,副研究员; Tel/Fax:0431-85262926; E-mail:jinrz@ciac.ac.cn; 研究方向:有机合成及聚酰亚胺合成
  • 基金项目:

    国家重点基础研究发展计划(973计划)课题(2014CB643603) 

    吉林省重大科技攻关专项(20140203003GX) 

    吉林省自然科学基金(20130101005JC)资助 

摘要: 报道了一种从卤代邻二甲苯偶联和液相氧化制备2,3,3',4'-联苯四甲酸二酐(3,4'-BPDA)的简便方法。以NiF2-PPh3(PPh3:三苯基膦)为催化体系,高效地实现了4-溴邻二甲苯格氏试剂与3-氯代邻二甲苯的交叉偶联反应,合成了2,3,3',4'-四甲基联苯(3,4'-TMDP),后者经液相氧化、高温脱水成酐制备了3,4'-BPDA,两步总产率达到74%。这条路线与从邻苯二甲酸二甲酯或混合氯代邻苯二甲酸二甲酯制备3,4'-BPDA相比,不涉及酯的水解及异构体的分离等过程,因此分离及环保方面具有非常明显的优势,同时合成路线更简便。

English

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  • 收稿日期:  2015-11-16
  • 网络出版日期:  2016-03-02
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