Synthesis of new 4,6-diaryl-2-(arylthio)nicotinonitriles in Triton X-100 aqueous micellar media

Citation: Mohammad Reza Poor Heravi, Amir Soufi. Synthesis of new 4,6-diaryl-2-(arylthio)nicotinonitriles in Triton X-100 aqueous micellar media[J]. Chinese Chemical Letters, 2015, 26(2): 263-266. doi: 10.1016/j.cclet.2014.11.007 shu

Synthesis of new 4,6-diaryl-2-(arylthio)nicotinonitriles in Triton X-100 aqueous micellar media

Mohammad Reza Poor Heravi ^, ,
Amir Soufi

通讯作者: Mohammad Reza Poor Heravi,

摘要: In this communication, we report four component condensations of acetophenone, arylaldehydes, arylthiol, and malononitrile in the presence of Triton X-100 (5 mol%) aqueous micelles. This reaction led to the formation of 4,6-diaryl-2-(arylthio)nicotinonitrile new derivatives in good yields. The FT-IR, ¹⁹F NMR, ¹H NMR, ¹³C NMR spectra and elemental analysis confirm the structure of compounds.

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