Synthesis of thiourea derivatives as CCR4 antagonists

Fang Zhao Jun Hai Xiao Ying Wang Song Li

引用本文: Fang Zhao,  Jun Hai Xiao,  Ying Wang,  Song Li. Synthesis of thiourea derivatives as CCR4 antagonists[J]. Chinese Chemical Letters, 2009, 20(3): 296-299. doi: 10.1016/j.cclet.2008.11.029 shu
Citation:  Fang Zhao,  Jun Hai Xiao,  Ying Wang,  Song Li. Synthesis of thiourea derivatives as CCR4 antagonists[J]. Chinese Chemical Letters, 2009, 20(3): 296-299. doi: 10.1016/j.cclet.2008.11.029 shu

Synthesis of thiourea derivatives as CCR4 antagonists

  • 基金项目:

    We appreciate PKU human disease genomics center for their unconditional support. This work was financially supported by the National High-Tech Research and Development Program of China (863 Program) (No. 2006AA10A201) and National Natural Science Foundation (No. 30472093).

摘要: A series of thiourea derivatives have been synthesized. Their structures were confirmed by MS and 1H NMR. Several compounds showed potent activities as antagonists of CCR4 receptor.

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  • 收稿日期:  2008-09-03
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