Synthesis of 14-epi-19-nor-22-oxa-1α, 25-dihydroxyvitamin D3

Wei Fan Li Hai Yong Wu

引用本文: Wei Fan,  Li Hai,  Yong Wu. Synthesis of 14-epi-19-nor-22-oxa-1α, 25-dihydroxyvitamin D3[J]. Chinese Chemical Letters, 2008, 19(3): 259-260. doi: 10.1016/j.cclet.2007.12.018 shu
Citation:  Wei Fan,  Li Hai,  Yong Wu. Synthesis of 14-epi-19-nor-22-oxa-1α, 25-dihydroxyvitamin D3[J]. Chinese Chemical Letters, 2008, 19(3): 259-260. doi: 10.1016/j.cclet.2007.12.018 shu

Synthesis of 14-epi-19-nor-22-oxa-1α, 25-dihydroxyvitamin D3

  • 基金项目:

    This work was supported by the National Natural Science Foundation of China (No. 29972013).

摘要: The synthesis of 14-epi-19-nor-22-oxa-1α, 25(OH)2D3 5 was started from diol 8 via Fall's method, oxidation, epimerization, protection, coupling with the 19-nor-A-ring 7, and then deprotection of the hydroxyl functions.

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  • 收稿日期:  2007-09-04
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