引用本文:
Wei ZHANG, Ni SONG, Zhong Zhen LI, Ying Xia LI. Synthesis of Obyanamide, a Marine Cytotoxic Cyclic Depsipeptide[J]. Chinese Chemical Letters,
2006, 17(3): 285-288.
Citation: Wei ZHANG, Ni SONG, Zhong Zhen LI, Ying Xia LI. Synthesis of Obyanamide, a Marine Cytotoxic Cyclic Depsipeptide[J]. Chinese Chemical Letters, 2006, 17(3): 285-288.
Citation: Wei ZHANG, Ni SONG, Zhong Zhen LI, Ying Xia LI. Synthesis of Obyanamide, a Marine Cytotoxic Cyclic Depsipeptide[J]. Chinese Chemical Letters, 2006, 17(3): 285-288.
Synthesis of Obyanamide, a Marine Cytotoxic Cyclic Depsipeptide
摘要:
The synthesis of a marine cytotoxic cyclic depsipeptide obyanamide has been accomplished. The key steps include assembling liner pentapeptide via Yamaguchi esterification and HATU-promoted ring closing. The structure of the synthetic sample was identified by 1H and 13C NMR, H-H COSY, HMQC, HMBC, and HRESIMS, but appears to be different from that of the marine natural product.
-
关键词:
- Obyanamide
- / synthesis
- / cyclic depsipeptide
- / natural product
English
Synthesis of Obyanamide, a Marine Cytotoxic Cyclic Depsipeptide
Abstract:
The synthesis of a marine cytotoxic cyclic depsipeptide obyanamide has been accomplished. The key steps include assembling liner pentapeptide via Yamaguchi esterification and HATU-promoted ring closing. The structure of the synthetic sample was identified by 1H and 13C NMR, H-H COSY, HMQC, HMBC, and HRESIMS, but appears to be different from that of the marine natural product.
-
Key words:
- Obyanamide
- / synthesis
- / cyclic depsipeptide
- / natural product
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 0
- HTML全文浏览量: 0
下载:
