Synthesis of Photoactivatable Phospholipidic Probes

Qing PENG Fan Qi QU Yi XIA Jie Hua ZHOU Qiong You WU Ling PENG

引用本文: Qing PENG,  Fan Qi QU,  Yi XIA,  Jie Hua ZHOU,  Qiong You WU,  Ling PENG. Synthesis of Photoactivatable Phospholipidic Probes[J]. Chinese Chemical Letters, 2005, 16(3): 349-352. shu
Citation:  Qing PENG,  Fan Qi QU,  Yi XIA,  Jie Hua ZHOU,  Qiong You WU,  Ling PENG. Synthesis of Photoactivatable Phospholipidic Probes[J]. Chinese Chemical Letters, 2005, 16(3): 349-352. shu

Synthesis of Photoactivatable Phospholipidic Probes

  • 基金项目:

    We thank Professor Andre Samat for giving us access to the irradiation equipment, Dr. Arnault Heynderickx and Mr. Daniel Compese for their help with the irradiation experiments, and Dr. Jessica Blanc for revising the English manuscript. Financial support from the National Key Project for Basic Research 2003CB114400, the Hi-Tech Research and Development Program of China No. 2003AA2Z3506, Wuhan University and the CNRS is gratefully acknowledged.

摘要: We synthesized and characterized photoactivatable phospholipidic probes 1-3. These probes have the perfluorinated aryl azide function at the polar head of phospholipid. They are stable in dark and become highly reactive upon photoirradiation. The preliminary results suggest that they are promising tools to study the topology of membrane proteins and protein-lipid interactions using photolabeling approach.

English

  • 加载中
计量
  • PDF下载量:  0
  • 文章访问数:  0
  • HTML全文浏览量:  0
文章相关
  • 收稿日期:  2004-03-08
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

/

返回文章