Total Synthesis of (±)Chrysotricine

Guang Xing WANG Shu Feng CHEN Xiao Tian LIANG

引用本文: Guang Xing WANG,  Shu Feng CHEN,  Xiao Tian LIANG. Total Synthesis of (±)Chrysotricine[J]. Chinese Chemical Letters, 1998, 9(4): 357-360. shu
Citation:  Guang Xing WANG,  Shu Feng CHEN,  Xiao Tian LIANG. Total Synthesis of (±)Chrysotricine[J]. Chinese Chemical Letters, 1998, 9(4): 357-360. shu

Total Synthesis of (±)Chrysotricine

  • 基金项目:

    We thank the National Research Center for Analysis of Drugs and Metabolites for recording of NMR and MS. We are also grateful to Prof. Xiao-Zhang Feng for a sample of the natural chrysotricine.

摘要: (±)Chrysotricine 1 was synthesized by a facile route. The key steps in the synthesis were aldol condensation of dilithium salt of harman 4 with 6-methyl-5-hepten-2-one 5 and cyclization of compound 6 using MCPBA. The 1HNMR spectrum of synthetic product was identical to that of the natural sample.

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  • 收稿日期:  1997-12-22
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