引用本文:
Zi Yi ZHANG, Yu Xiang LIANG, Zuo Wu GUAN. Studies on Semisynthesis and Anibacterial Activity of 7 β-(5-Methyl-1-Aryl-1H-1,2,3-Triazoly-4-Carboxamido) Cephalosporins[J]. Chinese Chemical Letters,
1997, 8(4): 295-298.
Citation: Zi Yi ZHANG, Yu Xiang LIANG, Zuo Wu GUAN. Studies on Semisynthesis and Anibacterial Activity of 7 β-(5-Methyl-1-Aryl-1H-1,2,3-Triazoly-4-Carboxamido) Cephalosporins[J]. Chinese Chemical Letters, 1997, 8(4): 295-298.
Citation: Zi Yi ZHANG, Yu Xiang LIANG, Zuo Wu GUAN. Studies on Semisynthesis and Anibacterial Activity of 7 β-(5-Methyl-1-Aryl-1H-1,2,3-Triazoly-4-Carboxamido) Cephalosporins[J]. Chinese Chemical Letters, 1997, 8(4): 295-298.
Studies on Semisynthesis and Anibacterial Activity of 7 β-(5-Methyl-1-Aryl-1H-1,2,3-Triazoly-4-Carboxamido) Cephalosporins
摘要:
Nine new derivatives of 7 β-(5-methyl-1-aryl-1H-1,2,3-triazoly-4-carboxamido) cephalosporins were synthesized by acylation of 7 β-amino group of 7-ACA,7-ADCA and 7-ACT with 5-methyl-1-aryl-1H-1,2,3-triazoly-4-formyl chloride.The structure of the compounds were confirmed by elementary analysis IR,1HNMR and FAB-MS.Some of them showed significant antibacterial activity.
English
Studies on Semisynthesis and Anibacterial Activity of 7 β-(5-Methyl-1-Aryl-1H-1,2,3-Triazoly-4-Carboxamido) Cephalosporins
Abstract:
Nine new derivatives of 7 β-(5-methyl-1-aryl-1H-1,2,3-triazoly-4-carboxamido) cephalosporins were synthesized by acylation of 7 β-amino group of 7-ACA,7-ADCA and 7-ACT with 5-methyl-1-aryl-1H-1,2,3-triazoly-4-formyl chloride.The structure of the compounds were confirmed by elementary analysis IR,1HNMR and FAB-MS.Some of them showed significant antibacterial activity.
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