引用本文:
安悦, 周光华, 邢永恒, 牟萍萍, 胡皆汉. 5-苯基-1H-3-吡唑酰腙化合物的合成及其结构表征[J]. 应用化学,
2008, 25(5): 539-542.
Citation: AN Yue, ZHOU Guang-Hua, XING Yong-Heng, MU Ping-Ping, HU Jie-Han. Synthesis and Structure Characterization of 5-Phenyl-1H-3-Pyrazole Hydrazones[J]. Chinese Journal of Applied Chemistry, 2008, 25(5): 539-542.
Citation: AN Yue, ZHOU Guang-Hua, XING Yong-Heng, MU Ping-Ping, HU Jie-Han. Synthesis and Structure Characterization of 5-Phenyl-1H-3-Pyrazole Hydrazones[J]. Chinese Journal of Applied Chemistry, 2008, 25(5): 539-542.
5-苯基-1H-3-吡唑酰腙化合物的合成及其结构表征
摘要:
采用"一锅法"合成了5-苯基-1H-3-吡唑甲酸乙酯,进而合成了9种5-苯基-1H-3-吡唑酰腙化合物,通过元素分析、红外光谱、核磁共振氢谱等测试技术对这9个化合物的结构进行了表征。将5-苯基-1H-3-吡唑甲酸乙酯水解得到5-苯基-1H-3-吡唑甲酸,此化合物与Cu(AcO)2配位,得到一个铜的三核配合物晶体,该晶体属单斜晶系,空间群为C2/c,晶胞参数为a=2.5767(3) nm,b=1.1944(1) nm,c=1.4127(2) nm,β=98.993(2)°,V=4.2941(9) nm3,Z=4,Dc=1.629 g/cm3,R1=0.0355,结果更进一步确定了吡唑环的结构。
English
Synthesis and Structure Characterization of 5-Phenyl-1H-3-Pyrazole Hydrazones
Abstract:
Ethyl 5-phenyl-1H-pyrazole-3-carboxylate was synthesized by one-pot reaction method,and was used further for the synthesis of nine 5-phenyl-1H-3-pyrazole hydrazones,which were characterized by elemental analysis,IR and 1H NMR.Furthermore,a trinuclear copper complex was obtained in the monoclinic space group of C2/c with cell dimensions of a=2.576 7(3) nm,b=1.194 42(15) nm,c=14.126 5(17) nm,β=98.993(2)°,V=4.294 1(9) nm3,Z=4,Dc=1.629 g/cm3 and R1=0.035 5 by the reaction of Cu(AcO)2 and 5-phenyl-1H-pyrazole-3-carboxylic acid which was obtained by hydrolysis of ethyl 5-phenyl-1H-pyrazole-3-carboxylate,and as a result the molecular structure of pyrazole was confirmed.
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Key words:
- pyrazole
- / hydrazones
- / phenyl-H-pyrazole carboxylic acid
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