Citation: Ping TONG, Jiang-Meng WU, Ping XU, Xiao-Ying WANG, Hai-Nan LI, Cheng WANG, Si-Qi YANG, Jia-Hui ZHOU, Rui-Bo XU. Syntheses, Crystal Structures, and Properties of Binuclear Copper(Ⅱ) Complexes Derived from 2-Aminopyridines[J]. Chinese Journal of Inorganic Chemistry, ;2022, 38(7): 1309-1316. doi: 10.11862/CJIC.2022.149 shu

Syntheses, Crystal Structures, and Properties of Binuclear Copper(Ⅱ) Complexes Derived from 2-Aminopyridines

College of Pharmacy, Jiangsu Ocean University, Lianyungang, Jiangsu 222005, China

Corresponding author: Hai-Nan LI, lihainan2007@126.com Rui-Bo XU, xuruibo9125@163.com
Received Date: 21 January 2022
Revised Date: 16 April 2022

Figures(10)

3-Methyl-2-aminopyridine (L₁) and 5-bromo-2-aminopyridine (L₂) were used as ligands respectively, and two novel binuclear copper(Ⅱ) complexes, [Cu₂(CH₃COO)₄(L₁)₂] (1) and[Cu₂(CH₃COO)₄(L₂)₂] (2), have been synthesized by the reaction of the above-mentioned ligands with anhydrous cupric acetate in ethanol solution. The two copper(Ⅱ)complexes were characterized by the methods of melting point, FT -IR, UV -Vis, fluorescence spectra, and HRMS. The crystal structures of 1 and 2 were analyzed by single-crystal X-ray diffraction, which indicates that 1 crystallizes in the orthorhombic system with Pbca space group, while 2 crystallizes in the monoclinic system with P2₁/n space group. Each of the two binuclear Cu(Ⅱ) complexes contains two copper center cations, four acetate ions, and two L₁ or L₂ ligands. Each acetate acts as a bridging ligand and coordinates to two Cu(Ⅱ) cations forming a cagelike structure. Each Cu(Ⅱ) cation in complexes 1 or 2 is pentacoordinate to one N atom in one pyridine ring and four O atoms in four acetate ions, and the geometries around Cu(Ⅱ) in 1 or 2 are distorted square pyramid. The antibacterial activities of 1 and 2 were investigated by the agar diffusion method, and the result indicated that 1 and 2 had good antibacterial inhibiting effects against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. And their antioxidant activities were valued using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH·) method, which showed that both of them possessed good scavenging capability on DPPH·. Moreover, the electrochemical properties of 1 and 2 were studied by the cyclic voltammetry method, and the results indicate that 1 and 2 showed quasi-reversible redox processes.
- binuclear copper(Ⅱ)complexes,
- amino pyridines,
- crystal structure,
- electrochemical property,
- bioactivity
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