Citation: XIAO Xin-Li, KONG De-Yan, ZHANG Ju-Sheng. Morphologically Controlled Synthesis of Hydroxyapatite at Mild Conditions[J]. Chinese Journal of Inorganic Chemistry, ;2016, 32(2): 289-296. doi: 10.11862/CJIC.2016.038 shu

Morphologically Controlled Synthesis of Hydroxyapatite at Mild Conditions

Department of Chemistry, Harbin Institute of Technology, Harbin 150001, China

Corresponding author: KONG De-Yan, dykong@hit.edu.cn
Received Date: 17 May 2015
Revised Date: 18 December 2015

Figures(6)

Simple methods are introduced to obtain hydroxyapatite (HAP, Ca10(PO₄)6(OH)2) nanocrystals with different structures and morphologies at mild conditions. The precipitation-hydrolysis two-step method can produce CaHPO₄ precursor by assistance of polyethylene glycol (PEG) and polyvinylpyrrolidone (PVP) during the precipitation step, and the hydrolysis of CaHPO₄ at 100 ℃ under atmospheric pressure leads to the formation of highly crystalline rod-like HAP nanocrystals. The HAP nanorods prepared with PEG possess uniform morphology with high aspect ratio while those prepared with PVP have smaller size with broader size distribution. One-step precipitation method can produce HAP directly, and the nanocrystals prepared with PEG are like wheat ears, while those prepared with PVP were composed of small nanoparticles and nanorods. The morphology of HAP samples was influenced by the organic additives, because the surfactants stabilized and confined the formation and growth of HAP nanocrystals. The morphology and structure of HAP nanoparticles changed greatly via the difference synthetic methods. Therefore, the controlling synthesis of HAP can be achieved by the change of synthetic conditions. The obtained HAP nanoparticles will be applicable for the future biomedical applications.
- precipitation-hydrolysis method,
- direct precipitation method,
- morphology controlling,
- hydroxyapatite
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沈阳化工大学材料科学与工程学院沈阳 110142